Snippet 29 - IgG4-Related Disease

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CT Chest ReviewBhavin Jankharia

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IgG4-related disease is an autoimmune process with infiltration of IgG4-plasma cells into tissues. It typically presents as a multi-organ, multicompartmental disease process.

The lung findings are myriad but often non-specific and it is not easy to make a prospective diagnosis, unless there are other organs like the lacrimal glands, salivary glands, pancreas, kidneys, aorta, etc involved.

This video goes through multi-system IgG4-related disease in general and then specifically looks at pulmonary and extra-pulmonary manifestations.