The New Acute Exacerbation White Paper and the Concept of "Replacement Fibrosis"

Diffuse alveolar damage (DAD) has many manifestations depending on the extent of injury and goes from an exudative phase to a phase of organization and then healing/repair, which have different appearances

Bhavin Jankharia

18 Aug 2026

Case:

This was published as a Youtube Case of the Day 219.

50-year-old presented with acute dyspnea on the background of progressive dyspnea 8 months back,

The ground glass represents acute exacerbation

Repeat scan 3 months later shows progression of disease

As if the ground glass has been replaced by fibrosis

The video discusses the following

The case
The new white paper on acute exacerbation in fibrotic ILDs
Diffuse alveolar damage and its temporal evolutio

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Index and Table of Contents

116 Cases with Videos
11 Cases with Posts
31 Snippets
16 Lectures
43 Cases of the Day (CODs)
New Series - ILD Patterns (4 Done)

Index and Table of Contents

Technical and Practice Issues * Case 11: 62-years old misdiagnosed to have interstitial lung disease - mid-inspiratory and expiratory scans * Snippet 03: Radiation risk and CT chest * Case 23: 60-years old - 40-pack years smoker - right upper lobe nodule - resolved using “mean” reconstructions…

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ILD Diffuse Alveolar Damage