Snippet 27: Airspace Enlargement with Fibrosis (AEF)

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CT Chest ReviewBhavin Jankharia

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Airspace enlargement with fibrosis (AEF) is non a well-known entity. It has been described only in smokers and often labeled as or considered part of smoking related interstitial fibrosis (AEF).

I first described this in snippet 13, when I enumerated the various findings that occur in smokers.

Snippet 13: Spectrum of Smoking Related Lung Changes in a Single Patient

The spectrum of lung changes in a smoker

CT Chest ReviewBhavin Jankharia

Recently, I saw AEF in a never-smoker and described it briefly.

Probably the best description of this subject is in this paper.

The video describes the entity and the "stalactite and stalagmite" sign, discusses how to diagnose it and differentiate it from honeycombing and emphysema along with the relevance and prognosis of making this diagnosis.