COD 174 - Scleroderma and FANO

Early changes and FANO

Bhavin Jankharia

Index and Table of Contents

116 Cases with Videos
4 Cases with Images
30 Snippets
16 Lectures
32 Cases of the Day (CODs)
New Series - ILD Patterns (2 Done)

Index and Table of Contents
Technical and Practice Issues * Case 11: 62-years old misdiagnosed to have interstitial lung disease - mid-inspiratory and expiratory scans * Snippet 03: Radiation risk and CT chest * Case 23: 60-years old - 40-pack years smoker - right upper lobe nodule - resolved using “mean” reconstructions…

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Case

33-years old with scleroderma and scleroderma ILD with a fibrotic non-specific interstitial pneumonia (NSIP) pattern.

The upper lobes show interstitial lesions, typically considered to be part of the NSIP pattern.

A recent Japanese paper introduces the concept of FANO - faint amorphous nodular opacities - first described with asbestosis, which are seen typically in the anterolateral non-dependent upper lobes and most commonly associated with an NSIP pattern and are known to progress and likely represent early-stage interstitial disease.

Case of the Day - 095 - 2025 09 03 - The Dots and Bands of Early Asbestosis
In patients with asbestos exposure, early asbestosis presents in a distinctive manner...however these signs do not help distinguish asbestosis from other ILDs if history of exposure is not known.

This brings to focus the likelihood that the early stage scleroderma ILD cases I have shown earlier have also likely been FANO lesions.

Case 94: How Early is Early...
What do these findings in a patient with scleroderma signify?

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